Dr. Suraj Chiraniya Hematologist & BMT Physician

What are the tests in sickle cell anemia?

Various tests are used to diagnose and monitor sickle cell anemia and its complications. Here are some common tests associated with this condition:

• #Hemoglobin Electrophoresis: This blood test helps identify the type of hemoglobin in a person's blood, including the presence of hemoglobin S (HbS) which is characteristic of sickle cell anemia.
• #Complete Blood Count (CBC): This test measures the number of red blood cells, white blood cells, and platelets in the blood. It can detect anemia and changes in blood cell counts.
• #Sickledex or Solubility Test: This quick screening test can detect the presence of HbS in the blood. If positive, further confirmatory tests are usually performed.
• #Peripheral Blood Smear: A blood sample is examined under a microscope to check for the presence of sickle-shaped red blood cells, which is a hallmark of the disease.
• #Genetic Testing: Genetic testing can confirm the presence of the sickle cell gene and identify specific mutations.
• #Hemoglobin Fractionation: This test can provide detailed information about the different types of hemoglobin in a person's blood, including HbS and fetal hemoglobin (HbF).
• #Hemoglobin A1c: This test measures the average blood sugar level over the past 2-3 months and can help monitor the risk of diabetes, which can be higher in people with sickle cell anemia.
• #Imaging Studies: X-rays, ultrasounds, or MRI scans may be used to assess complications such as organ damage, strokes, or joint problems.
• #Pain Assessment: Assessing the frequency and severity of pain crises is crucial for managing sickle cell anemia. Patients often rate their pain on a scale to guide treatment.